CBD works by interacting with the endocannabinoid system (ECS), which is a network of receptors and signaling pathways found throughout the body involved in a variety of physiological processes, including pain, mood, appetite, and memory.
The cannabinoid receptors 1 (CB1) and cannabinoid receptors 2 (CB2) are proteins found on the surface of cells throughout the body. They are part of the endocannabinoid system (ECS), which is a network of receptors and signaling pathways
CB1 receptors are primarily found in the central nervous system (brain and spinal cord) and are involved in the regulation of mood, memory, and pain perception. They are also found in the peripheral nervous system, which includes the nerves that extend from the brain and spinal cord to the rest of the body. When THC binds to CB1 receptors in the brain, it can produce a range of effects, including altered perception, mood changes, and impaired cognitive function. CB1 receptors are also involved in the regulation of other physiological processes, such as energy balance, immune function, and cardiovascular function. In addition to THC, there are other cannabinoids that can bind to CB1 receptors, including CBD (cannabidiol) and CBG (cannabigerol).
CB2 receptors are primarily found in the immune system and are involved in the regulation of inflammation. They are also found in the peripheral nervous system, as well as in the gastrointestinal system, spleen, and other organs. When THC binds to CB2 receptors, it can produce a range of effects, including altered immune function, inflammation, and pain sensation. In addition to THC, there are other cannabinoids that can bind to CB2 receptors, including CBD (cannabidiol) and CBG (cannabigerol). Unlike THC, these cannabinoids do not produce psychoactive effects when they bind to CB2 receptors.
When activated by endocannabinoids or plant-derived cannabinoids like CBD or THC, CB1 and CB2 receptors can help to regulate various bodily functions. However, more research is needed to fully understand the specific roles of these receptors and how they interact with CBD and other cannabinoids.
